Visualizing a two-state conformational ensemble in stem-loop 3 of the transcriptional regulator 7SK RNA
M. B. Camara, B. Lange, J. D. Yesselman, C. D. Eichhorn
The paper integrates NMR spectroscopy and chemical probing to visualize a two-state conformational ensemble in stem-loop 3 of 7SK RNA, showing structural dynamics and state conservation across vertebrates.
bioRxiv · Aug 9, 2023Biophysics