The SARS-CoV-2 nucleocapsid protein preferentially binds long and structured RNAs
C. E. Tai, E. Tayeb-Fligelman, S. Griner, L. Salwinski, J. T. Bowler, R. Abskharon, X. Cheng, P. M. Seidler, Y. X. Jiang, D. S. Eisenberg, F. Guo
This study investigates how SARS-CoV-2 nucleocapsid protein binds RNA, finding it preferentially interacts with structured and long RNAs, and proposes a mechanism linking packaging to RNA recognition.
bioRxiv · Dec 25, 2021 · PreprintBiochemistry