The mechanistic basis for chromatin invasion and remodeling by the yeast pioneer transcription factor Rap1
M. Mivelaz, A.-M. Cao, S. Kubik, S. Zencir, R. Hovius, I. Boichenko, A. M. Stachowicz, C. F. Kurat, D. Shore, B. Fierz
This study reveals how the yeast pioneer transcription factor Rap1 invades and remodels chromatin by opening fiber structure and collaborating with RSC to destabilize promoter nucleosomes.
bioRxiv · Jul 9, 2019Biophysics