Personalized models of breast cancer desmoplasia reveal biomechanical determinants of drug penetration
G. S. Offeddu, E. Cambria, S. E. Shelton, Z. Wan, K. Haase, L. Possenti, H. T. Nguyen, M. R. Gillrie, D. Hickman, C. G. Knutson, R. D. Kamm
The paper develops personalized breast cancer models to identify biomechanical factors affecting drug penetration and discovers potential therapeutic targets.
bioRxiv · Dec 12, 2021Bioengineering