Author

L. Possenti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Cicchetti· 1 shared C. G. Knutson· 1 shared D. Hickman· 1 shared E. Cambria· 1 shared G. S. Offeddu· 1 shared H. T. Nguyen· 1 shared K. Haase· 1 shared M. R. Gillrie· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioengineering

A. Cicchetti

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Author profile →

2 papers

Recent·Most cited

Microvascular morphology affects radiotherapy outcomes: a computational study

L. Possenti, P. Vitullo, A. Cicchetti, P. Zunino, T. Rancati

This study uses computational models to show that microvascular density and regularity influence radiation therapy outcomes by shaping hypoxia, with carbon-based hadron therapy showing potential to overcome hypoxia resistance.

bioRxiv · Oct 16, 2023Bioengineering

Personalized models of breast cancer desmoplasia reveal biomechanical determinants of drug penetration

G. S. Offeddu, E. Cambria, S. E. Shelton, Z. Wan, K. Haase, L. Possenti, H. T. Nguyen, M. R. Gillrie, D. Hickman, C. G. Knutson, R. D. Kamm

The paper develops personalized breast cancer models to identify biomechanical factors affecting drug penetration and discovers potential therapeutic targets.

bioRxiv · Dec 12, 2021Bioengineering