Author

C. Guet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:DNA methylation· 1 Research Focus:ecology & biodiversity· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:sequence-to-function modeling· 1

Frequent Co-Authors

M. Pleska· 2 shared G. Tkacik· 1 shared I. Tomanek· 1 shared J. Ruess· 1 shared N. Nikolic· 1 shared T. Bergmiller· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 6 mutual co-author links

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2 shared papersMicrobiology

M. Pleska

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Bacterial toxin-antitoxin system MazEF as a native defense mechanism against RNA phages in Escherichia coli

N. Nikolic, T. Bergmiller, M. Pleska, C. Guet

This study shows that the MazEF toxin-antitoxin system in E. coli protects against RNA phages by cleaving their genomes, with MazF targeting specific sequences in phage genomes.

bioRxiv · Feb 1, 2023Microbiology

The adaptation dynamics between copy-number and point mutations

I. Tomanek, C. Guet

This study examines how copy-number and point mutations adapt in Escherichia coli, finding they follow different dynamics based on gene expression demand.

bioRxiv · Aug 11, 2022Evolutionary Biology

Molecular noise of innate immunity shapes bacteria-phage ecologies

J. Ruess, M. Pleska, C. Guet, G. Tkacik

This study uses mathematical models to show how molecular stochasticity in bacterial immunity affects population-level ecological outcomes and optimal defense strategies against phages.

bioRxiv · Jan 15, 2019Biophysics