N. Nikolic

Investigating bacteria-phage interaction dynamics using droplet-based technology

This study uses droplet microfluidics and fluorescence microscopy to analyze bacterial-phage interactions in E. coli, revealing growth and lysis dynamics of phage-infected cells.

Label-free analysis of bacterial growth and lysis at the single-cell level using droplet microfluidics and object detection-oriented deep learning

This paper develops a label-free method using microfluidics and YOLOv4 deep learning to count and track single bacterial cells and study phage interactions.

Bacterial toxin-antitoxin system MazEF as a native defense mechanism against RNA phages in Escherichia coli

This study shows that the MazEF toxin-antitoxin system in E. coli protects against RNA phages by cleaving their genomes, with MazF targeting specific sequences in phage genomes.

Real-time dynamics of individual chemoreceptor mRNA molecules reveals translation hotspots at the inner membrane of Escherichia coli

The paper tracks individual mRNA molecules in live E. coli to show membrane protein translation occurs in localized hotspots near the inner membrane.

Nutrient and salt depletion synergistically boosts glucose metabolism in individual bacteria

This study shows that nutrient and salt depletion in E. coli increases glucose accumulation rates at the translational and posttranslational levels, challenging the view that growth rate alone reflects metabolic status.