Author

C. H. Birkenheuer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:virus· 1

Frequent Co-Authors

J. D. Baines· 2 shared L. E. M. Dunn· 1 shared R. Dufour· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersMicrobiology

J. D. Baines

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2 papers

Recent·Most cited

MicrobiologybioRxivJun 13, 2022

Immediate early proteins of herpes simplex virus transiently repress viral transcription before subsequent activation

L. E. M. Dunn, C. H. Birkenheuer, R. Dufour, J. D. Baines

This study shows HSV-1 immediate early genes initially repress viral transcription before activating it, revealing a repressive phase in the lytic transcriptional cascade.

DOI 10.1128/jvi.01416-22

experimental assay

𝕏 PostBluesky

MicrobiologybioRxivMay 5, 2021

The ICP22 protein of Herpes Simplex Virus 1 promotes RNA Polymerase II activity on Viral Immediate Early Genes

C. H. Birkenheuer, J. D. Baines

This study shows that HSV-1 ICP22 enhances RNA Polymerase II activity on viral immediate early genes, promoting transcription initiation and elongation, and is critical for sustaining viral DNA replication and later stages of infection.

DOI 10.1128/jvi.02191-21

virusDNA methylation

𝕏 PostBluesky