Author

C. H. McFadden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

D. B. Flint· 2 shared D. Ohsawa· 2 shared G. O. Sawakuchi· 2 shared S. F. Shaitelman· 2 shared S. J. Bright· 2 shared T. Konishi· 2 shared A. Kobayashi· 1 shared B. X. Turner· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersBiophysics

D. B. Flint

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2 papers

Recent·Most cited

An empirical model to predict survival curve and relative biological effectiveness after helium and carbon ion irradiation based solely on the cell survival after photon irradiation

D. B. Flint, S. J. Bright, C. H. McFadden, T. Konishi, D. Ohsawa, A. Kobayashi, S. F. Shaitelman, G. O. Sawakuchi

The paper develops an empirical model to predict ion radiosensitivity, RBE, and survival curves using photon irradiation data across a range of LET values.

bioRxiv · Jun 19, 2020 · PreprintBiophysics

Cell lines of the same anatomic site and histologic type show large variability in intrinsic radiosensitivity and relative biological effectiveness to protons and carbon ions

D. B. Flint, S. J. Bright, C. H. McFadden, T. Konishi, D. Ohsawa, B. X. Turner, S. H. Lin, D. R. Grosshans, S. F. Shaitelman, H.-S. Chiu, P. Sumazin, G. O. Sawakuchi

This study shows that cancer cell lines from the same anatomic site and histologic type exhibit large variability in radiosensitivity and relative biological effectiveness to protons and carbon ions, attributed to differences in DNA repair capacity.

bioRxiv · Jun 19, 2020Biophysics