T. Konishi

Why do some fungi want to be sterile? The role of dysfunctional Pro1 in the rice blast fungus

The paper identifies a dysfunctional Pro1 gene as a cause of female sterility in the rice blast fungus, showing it may confer survival advantages.

King- and queen-specific degradation of uric acid is the key to reproduction in termites

The paper identifies king- and queen-specific uric acid degradation as critical for reproduction in termites, showing its role in nitrogen utilization for egg production.

Seasonal movement of royal chambers: where are the kings and queens of temperate termites in winter?

This study identifies an underground royal chamber used by termite kings and queens during winter, showing it helps avoid cold temperatures and mortality risks.

Study of aging using circuit tests and parametric analysis

The paper analyzes aging in mice using 11 circuit tests, finding that power decreases with age while accuracy peaks at 6 months, with the open field test showing the lowest noise and highest sensitivity.

SARS-CoV-2 mutations among minks show reduced lethality and infectivity to humans

The paper analyzes SARS-CoV-2 mutations in minks and finds some variants are less lethal and infective to humans compared to human-derived variants.

Progressing adaptation of SARS-CoV-2 to humans

This paper analyzes the mutation patterns of SARS-CoV-2 over time, identifying three major groups and showing how mutations increased infectivity and led to subsequent waves of COVID-19.

An empirical model to predict survival curve and relative biological effectiveness after helium and carbon ion irradiation based solely on the cell survival after photon irradiation

The paper develops an empirical model to predict ion radiosensitivity, RBE, and survival curves using photon irradiation data across a range of LET values.

Cell lines of the same anatomic site and histologic type show large variability in intrinsic radiosensitivity and relative biological effectiveness to protons and carbon ions

This study shows that cancer cell lines from the same anatomic site and histologic type exhibit large variability in radiosensitivity and relative biological effectiveness to protons and carbon ions, attributed to differences in DNA repair capacity.

Coronavirus, as a source of pandemic pathogens.

The paper compares coronavirus and influenza virus genome data to investigate spreading mechanisms and future pandemic potential, finding coronaviruses may spread repeatedly and have other pandemic candidates.

Linker histone H1 determines cell stiffness and differentiation

The paper shows that linker histone H1 quantity correlates with cell stiffness and affects cell size and differentiation.

Principal Component Analysis applied directly to Sequence Matrix

The paper applies PCA directly to sequence matrices to better analyze sequence data by converting it to boolean vectors, improving resolution and revealing directional differences and causative nucleotides.