Author

C. H. N. Costa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. J. Meneses Filho· 1 shared C. A. Grace· 1 shared C. d. M. Pedrozo e Silva de Azevedo· 1 shared C. Pagliari· 1 shared C. V. B. de Melo· 1 shared D. C. Jeffares· 1 shared D. L. Costa· 1 shared D. Speed· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPathology

A. J. Meneses Filho

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2 papers

Recent·Most cited

PathologybioRxivDec 21, 2023

Tittle: An integrated analysis of the structural changes and gene expression of spleen in human visceral leishmaniasis with and without HIV coinfection

J. L. M. Fontes, R. Khouri, L. G. C. Reinaldo…·W. L. C. dos-Santos

This study compares structural and gene expression changes in spleens of visceral leishmaniasis patients with and without HIV coinfection, identifying key pathways and gene associations linked to spleen disorganization.

DOI 10.1371/journal.pntd.0011877

humanbulk RNA-seq

𝕏 PostBluesky

Evolutionary BiologybioRxivJul 28, 2022

Parasite genotype is a major predictor of mortality from visceral leishmaniasis

C. A. Grace, K. S. Sousa Carvalho, M. I. Sousa Lima…·C. H. N. Costa

This study identifies parasite genotype as a major predictor of mortality from visceral leishmaniasis in Brazil, with heritability estimates up to 83% for mortality.

DOI 10.1128/mbio.02068-22

statistical modelhost-pathogen & immune response

𝕏 PostBluesky