Discovery of highly potent pancoronavirus fusion inhibitors that also effectively inhibit COVID-19 variants from the UK (Alpha), South Africa (Beta), and India (Delta)
F. Curreli, S. Ahmed, S. M. B. Victor, A. Drelich, S. S. Panda, A. Altieri, A. Kurkin, C.-T. Tseng, C. Hillyer, A. Debnath
The paper identifies potent small molecules that inhibit multiple coronaviruses, including SARS-CoV-2 variants, with high selectivity and in vivo efficacy.
bioRxiv · Sep 3, 2021Pharmacology & Toxicology