TMX5/TXNDC15, a natural trapping mutant of the PDI family is a client of the proteostatic factor ERp44
T. Solda, C. Galli, C. Guerra, C. Hoefner, M. Molinari
The paper identifies TMX5 as a PDI family member that interacts with ERp44 via disulfide bonds, controlling its ER retention and distribution.
bioRxiv · Jun 12, 2024Cell Biology