Author

C. Hofr

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:electronic health records· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

M. Stojaspal· 3 shared P. Veverka· 3 shared T. Janovic· 3 shared T. Brom· 2 shared D. Horakova· 1 shared I. Necasova· 1 shared J. Novacek· 1 shared L. Hernychova· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBiochemistry

M. Stojaspal

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3 papers

Recent·Most cited

Inherited CDA-I disease: anemia-associated mutations disrupt CDIN1-Codanin1 complex

M. Stojaspal, T. Brom, T. Janovic, I. Necasova, P. Veverka, N. Verma, L. Uhrik, L. Hernychova, C. Hofr

This study identifies how mutations in CDIN1 and CDAN1 disrupt the CDIN1-Codanin1 complex, contributing to CDA-I disease.

bioRxiv · May 25, 2023 · PreprintBiochemistry

Electron microscopy reveals toroidal shape of master neuronal cell differentiator REST - RE1-Silencing Transcription factor

P. Veverka, T. Brom, T. Janovic, M. Stojaspal, M. Pinkas, J. Novacek, C. Hofr

The paper uses electron microscopy to reveal the toroidal structure of REST and describes its DNA-binding properties and splicing variant interactions.

bioRxiv · Oct 6, 2022Biochemistry

Human telomere repeat binding factor TRF1 replaces TRF2 bound to shelterin core hub TIN2 when TPP1 is absent

C. Hofr, T. Janovic, M. Stojaspal, P. Veverka, D. Horakova

The paper uses single-molecule techniques to show TRF1 can replace TRF2 on TIN2 when TPP1 is absent, and TPP1 enables simultaneous binding of both TRF1 and TRF2 to TIN2.

bioRxiv · Oct 5, 2018Biochemistry