Click-PD: A Quantitative Method for Base-Modified Aptamer Discovery
C. K. L. Gordon, D. T. Wu, T. A. Feagin, A. Pusuluri, A. T. Csordas, M. Eisenstein, C. J. Hawker, J. Niu, H. T. Soh
This paper introduces click-PD, a method for discovering base-modified aptamers with high affinity and specificity using click chemistry and FACS screening.
bioRxiv · May 3, 2019 · PreprintBioengineering