Leaflet-specific phospholipid imaging using genetically encoded proximity sensors
W. M. Moore, R. J. Brea, C. Knittel, E. Wrightsman, B. Hui, J. Loui, C. F. Ancajas, M. D. Best, C. J. Obara, N. K. Devaraj, I. Budin
This paper introduces FACES, a tool for imaging lipid pools and transbilayer orientation in living cells, and applies it to study lipid transfer proteins and membrane asymmetry.
bioRxiv · May 1, 2024Cell Biology