USP28 and SPINT2 mediate cell cycle arrest after whole genome doubling
Z. Storchova, K. Seget-Trzensiok, S. V. Bernhard, C. Kuffer, D. B. Krastev, M. Theiss, K. Keuper, J.-E. Boekenkamp, M. Kschischo, F. Buchholz
The paper identifies USP28 and SPINT2 as factors that enable tetraploid cell survival by modulating cell cycle arrest and DNA damage responses.
bioRxiv · Sep 18, 2020 · PreprintCell Biology