Author

C. Levet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. Freeman· 3 shared A. Chikh· 1 shared A. Duchesne· 1 shared B. Zhang· 1 shared C. M. Webb· 1 shared D. P. Kelsell· 1 shared F. Charron· 1 shared I. Dulloo· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCell Biology

M. Freeman

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Eta-secretase-like processing of the amyloid precursor protein (APP) by RHBDL4

Y. C. M. Penalva, S. Paschkowsky, S. J. Recinto, A. Duchesne, C. Levet, F. Charron, M. Freeman, R. A. McKinney, J.-F. Trempe, L. M. Munter

This study identifies RHBDL4 as an enzyme that processes APP similarly to {eta}-secretase, generating A{eta}-like fragments in the ER without requiring other proteases.

bioRxiv · Sep 4, 2023 · PreprintBiochemistry

Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signalling pathway

I. Dulloo, M. Tellier, C. Levet, A. Chikh, B. Zhang, C. M. Webb, D. P. Kelsell, M. Freeman

The paper identifies a novel ER-to-nucleus signaling pathway mediated by iRhom2 cleavage by the signal peptidase complex, linking it to psoriasis and TOC.

bioRxiv · Nov 28, 2022 · PreprintCell Biology

RHBDL4 protects against endoplasmic reticulum stress by regulating the morphology and distribution of ER sheets

V. L. Lastun, C. Levet, M. Freeman

This study identifies RHBDL4 as a regulator of ER morphology and distribution, showing its protective role against ER stress without requiring enzymatic activity.

bioRxiv · Jun 15, 2021 · PreprintCell Biology