Author

C. M. Fridman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:virus· 1

Frequent Co-Authors

D. Salomon· 5 shared E. Bosis· 3 shared B. Jana· 2 shared R. Ben-Yaakov· 2 shared A. Carobbi· 1 shared G. Sessa· 1 shared H. Cohen· 1 shared I. Barash· 1 shared

Activity by Year

2021-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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5 shared papersMicrobiology

D. Salomon

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A new class of polymorphic T6SS effectors and tethers

K. Kanarek, C. M. Fridman, E. Bosis, D. Salomon

The paper identifies RIX as a new domain defining polymorphic T6SS effectors and tethers, expanding the known repertoire of T6SS cargo and suggesting a broader role in vibrio-eukaryote interactions.

bioRxiv · Oct 27, 2022Microbiology

Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors

H. Cohen, N. Baram, C. M. Fridman, L. Edry-Botzer, D. Salomon, M. Gerlic

The paper identifies two novel T6SS effectors from Vibrio that induce pyroptosis via NLRP3 inflammasome activation in mammalian immune cells and reveal a compensatory pathway.

bioRxiv · Aug 11, 2022Immunology

Multiple T6SSs, mobile auxiliary modules, and effectors revealed in a systematic analysis of the Vibrio parahaemolyticus pan-genome

B. Jana, K. Keppel, C. M. Fridman, E. Bosis, D. Salomon

The paper systematically analyzes the T6SS gene clusters and auxiliary modules in the Vibrio parahaemolyticus pan-genome, identifying diverse T6SS systems and novel effectors.

bioRxiv · Aug 2, 2022Microbiology

A DNase T6SS effector requires its MIX domain for secretion

C. M. Fridman, B. Jana, R. Ben-Yaakov, E. Bosis, D. Salomon

The paper identifies a DNase toxin domain in a Vibrio parahaemolyticus T6SS effector and shows its necessity for secretion and toxicity.

bioRxiv · May 4, 2022Microbiology

A dynamic antibacterial T6SS in Pantoea agglomerans pv. betae delivers a lysozyme-like effector to antagonize competitors

A. Carobbi, S. Di Nepi, C. M. Fridman, Y. Dar, R. Ben-Yaakov, I. Barash, D. Salomon, G. Sessa

This study identifies a functional T6SS in Pantoea agglomerans pv. betae that delivers a lysozyme-like effector to outcompete bacterial rivals.

bioRxiv · Dec 3, 2021Microbiology