Author

C. Maluquer de Motes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1 Research Focus:phylogenetics / evolution· 1 Assay:proteomics· 1

Frequent Co-Authors

R. P. Sumner· 3 shared G. J. Towers· 2 shared A. Ahmad· 1 shared A. Akinpelu· 1 shared A. Ellis· 1 shared A. Rambaut· 1 shared A. Yinka-Ogunleye· 1 shared B. Gannon· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMicrobiology

R. P. Sumner

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Type I IFN expression is inhibited during cell division by CDK4/6

R. P. Sumner, A. Ellis, S. Lant, H. Ashby, G. J. Towers, C. Maluquer de Motes

The paper shows that CDK4/6 inhibition enhances DNA- or cGAMP-induced IFN and ISG expression by limiting IFNβ mRNA production during cell division.

bioRxiv · Apr 15, 2023 · PreprintImmunology

A maturation defective HIV-1 activates cGAS

R. P. Sumner, H. Blest, M. Lin, C. Maluquer de Motes, G. J. Towers

The paper shows that a maturation-defective HIV-1 variant activates the cGAS pathway, leading to an IFN response due to exposed viral DNA.

bioRxiv · Apr 14, 2023 · PreprintMicrobiology

Different Coexisting Mpox Lineages Were Continuously Circulating in Humans Prior to 2022

N. D. Ndodo, J. Ashcroft, K. Lewandowski, A. Yinka-Ogunleye, C. Chukwu, A. Ahmad, D. King, A. Akinpelu, C. Maluquer de Motes, P. Ribeca, R. P. Sumner, A. Rambaut, M. Chester, T. Maishman, O. Bamidele, , D. Ulaeto

The paper identifies multiple coexisting Mpox lineages circulating in humans in Nigeria prior to the 2022 global outbreak, showing sustained human-to-human transmission and genetic changes.

bioRxiv · Jan 3, 2023 · PreprintMicrobiology

Beneficial bacteria activate type-I interferon production via the cytosolic sensors STING and MAVS

J. Gutierrez-Merino, B. Isla, T. Combes, F. O. Martinez-Estrada, C. Maluquer de Motes

This study shows that beneficial bacteria trigger type-I interferon production through STING and MAVS in macrophages, with specific strains inducing strong immune responses.

bioRxiv · Oct 4, 2019Immunology