Acetylation of cytidine residues boosts HIV-1 gene expression by increasing viral RNA stability
K. Tsai, A. A. J. Vasudevan, C. MartInez-Campos, A. Emery, R. Swanstrom, B. R. Cullen
This study shows HIV-1 transcripts are acetylated at cytidine residues by NAT10, enhancing viral RNA stability and gene expression, suggesting ac4C as a potential antiviral target.
bioRxiv · Jan 31, 2020Microbiology