Author

C. Mein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

J. Boot· 2 shared A. Goralcyzk· 1 shared C. Vinel· 1 shared D. El Abyad· 1 shared G. Hood· 1 shared H. Malik· 1 shared I. Gines Mir· 1 shared J. A. Fallowfield· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMolecular Biology

J. Boot

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Author profile →

2 papers

Recent·Most cited

TLR5 drives metabolic dysfunction-associated steatohepatitis through lipid- and flagellin-induced hepatocyte injury signalling

W. Li, N. Wang, R. Kumar, I. Gines Mir, U. Gill, G. Hood, J. Brindley, C. Mein, J. Boot, R. Wilcox, N. Dufton, R. Goldin, J. Loy, K. Devalia, H. Malik, , W. Alazawi

The paper investigates TLR5's role in MASH and fibrosis using clinical data, single-cell transcriptomics, and in vitro models, finding TLR5 drives hepatocyte injury and fibrosis through flagellin and lipid pathways.

bioRxiv · Feb 7, 2026 · PreprintMolecular Biology

Mapping chromatin remodelling in glioblastoma identifies epigenetic regulation of key molecular pathways and novel druggable targets.

C. Vinel, J. Boot, W. Jin, N. Pomella, C. Mein, R. Zabet, S. Marino

The paper identifies epigenetic regulation of key pathways and novel druggable targets in glioblastoma by comparing chromatin remodelling in neoplastic and neural stem cells.

bioRxiv · Feb 24, 2024Cancer Biology