ImmunologybioRxivPreprint
Somatic Mutations in Clonally Expanded T-lymphocytes in Patients with Chronic Graft-Versus-Host Disease
G. Park, S. Mustjoki, D. Kim…·M. A. I. Keranen
This study identifies somatic mutations in clonally expanded T-cells in chronic GvHD patients, showing they drive persistent activation and resistance to mTOR inhibitors.