CD47 prevents the elimination of diseased fibroblasts in scleroderma
T. Lerbs, L. Cui, M. King, T. Chai, C. Muscat, T. Shibata, G. Wernig
This study shows that CD47 protects scleroderma fibroblasts from immune elimination and that blocking CD47 with IL6 inhibition can reverse fibrosis in mice.
bioRxiv · Jun 6, 2020Immunology