Author

G. Wernig

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

L. Cui· 3 shared T. Lerbs· 3 shared A. C. Trotman-Grant· 1 shared C. Garcia· 1 shared C. Muscat· 1 shared C. V. Neste· 1 shared G. P. Nolan· 1 shared I. Moraga· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersImmunology

L. Cui

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Tuning TPO-R signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia

L. Cui, I. Moraga, T. Lerbs, C. V. Neste, S. Wilmes, N. Tsutsumi, A. C. Trotman-Grant, M. Gakovic, S. Andrews, J. Gotlib, S. Darmanis, M. Enge, S. Quake, I. S. Hitchcock, J. Piehler, , G. Wernig

This study develops diabody ligands that modulate TPO-R signaling, showing partial agonists preserve HSCs and inhibit ET oncogenesis.

bioRxiv · Sep 23, 2020Cell Biology

CD47 prevents the elimination of diseased fibroblasts in scleroderma

T. Lerbs, L. Cui, M. King, T. Chai, C. Muscat, T. Shibata, G. Wernig

This study shows that CD47 protects scleroderma fibroblasts from immune elimination and that blocking CD47 with IL6 inhibition can reverse fibrosis in mice.

bioRxiv · Jun 6, 2020Immunology

Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity

L. Cui, S.-Y. Chen, T. Lerbs, J.-W. Lee, P. Domizi, S. Gordon, Y.-h. Kim, G. P. Nolan, P. Betancur, G. Wernig

This study shows JUN activation in fibroblasts drives fibrosis and modulates immunity, with therapeutic potential through targeting IL-6, CD47, and PD-L1.

bioRxiv · Mar 18, 2020Immunology