Author

C. N. Chi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:protein folding & dynamics· 3 Organism:human· 2 Assay:protein structure· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A.-C. Lindas· 2 shared F. Hurtig· 2 shared S. R. Haq· 2 shared S. Survery· 2 shared B. Vogeli· 1 shared D. Ashkinadze· 1 shared D. Strotz· 1 shared H. Kadavath· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiophysics

A.-C. Lindas

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Author profile →

4 papers

Recent·Most cited

Atomic resolution Protein Allostery from the multi-state Structure of a PDZ Domain

D. Ashkinadze, H. Kadavath, C. N. Chi, M. Friedmann, D. Strotz, P. Kumari, M. Minges, R. Cadalbert, S. KÖnigl, P. Güntert, B. Vogeli, R. Riek

The paper determines multi-state structures of the PDZ2 domain using NMR to study protein allostery and conformational changes.

bioRxiv · Nov 23, 2021Biophysics

Structural characterization of a Thorarchaeota profilin indicates eukaryotic-like features but with an extended N-terminus

C. N. Chi, R. T. Inturi, S. M. Lara, M. Darweesh

The paper determines the structure of Thorarchaeota profilin, showing eukaryotic-like features with an extended N-terminus and co-localization with eukaryotic actin in HeLa cells.

bioRxiv · Aug 6, 2021Evolutionary Biology

NMR backbone assignment and dynamics of Profilin from Heimdallarchaeota

S. R. Haq, S. Survery, F. Hurtig, A.-C. Lindas, C. N. Chi

This study structurally characterizes profilin from Heimdallarchaeota, showing similarities and differences compared to eukaryotic profilin.

Scientific Reports · Sep 28, 2020Peer-reviewedBiophysics

Heimdallarchaea encodes profilin with eukaryotic-like actin regulation and polyproline binding

S. Survery, F. Hurtig, S. R. Haq, A.-C. Lindas, C. N. Chi

This paper identifies a profilin in Heimdallarchaeota that interacts with PIP2 and polyproline motifs, suggesting an origin predating eukaryotes and supporting a complex cytoskeleton in the Last Eukaryotic Common Ancestor.

bioRxiv · Apr 23, 2020Evolutionary Biology