Golgi localized β1-adrenergic receptors stimulate Golgi PI4P hydrolysis by PLCε to regulate cardiac hypertrophy
C. Nash, W. Wei, R. Irannejad, A. Smrcka
The paper identifies a pathway where Golgi localized β1-adrenergic receptors stimulate PI4P hydrolysis via PLCε to promote cardiac hypertrophy, distinct from surface receptor signaling.
bioRxiv · May 19, 2019Cell Biology