BiochemistrybioRxivPreprint
Orthoformimycin inhibits translation elongation by displacing the A-site tRNA and preventing peptide bond formation
A. Schedlbauer, T. Kaminishi, A. Fabbretti…·P. Fucini
This study investigates how orthoformimycin inhibits translation elongation by displacing the A-site tRNA and blocking peptide bond formation using X-ray crystallography and kinetic analysis.
DOI 10.1101/2021.11.29.470217