SLC4A11 mediates ammonia import and promotes cancer stemness in hepatocellular carcinoma
Ameer L. Elaimy, Marwa O. El-Derany, Jadyn G. James, Zhuwen Wang, Ashley N. Pearson, Erin A. Holcomb, Amanda K. Huber, Miguel A. Gijón, Hannah Noelle Bell, Viraj R. Sanghvi, Timothy L. Frankel, Grace L. Su, Elliot B. Tapper, Andrew W. Tai, Nithya Ramnath, , Michael D. Green
This study identifies SLC4A11 as a mediator of ammonia import in hepatocellular carcinoma, showing its role in promoting cancer stemness and tumor growth.
JCI Insight · Oct 22, 2024Peer-reviewedCancer Biology