Isolation and characterization of human monoclonal antibodies to pneumococcal capsular polysaccharide 3
R. Babb, C. R. Doyle, L.-a. Pirofski
This study isolates and characterizes human monoclonal antibodies against pneumococcal capsular polysaccharide 3, finding that agglutination and opsonophagocytic activity correlate with in vivo efficacy and that light chain variable region mutations affect function.
bioRxiv · Aug 2, 2021Microbiology