A dramatic impairment of the antitumor activity of human Vgamma9Vdelta2 T cells is induced by TGF-beta through significant phenotype, transcriptomic and metabolic changes
C. RAFIA, C. LOIZEAU, O. RENOULT, C. HARLY, C. PECQUEUR, N. JOALLAND, E. SCOTET
This study shows TGF-beta impairs Vgamma9Vdelta2 T cell antitumor activity through phenotypic, transcriptomic, and metabolic changes in vitro.
bioRxiv · Sep 22, 2022 · PreprintImmunology