Author

E. Scotet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Barjon· 1 shared C. HARLY· 1 shared C. LOIZEAU· 1 shared C. PECQUEUR· 1 shared C. RAFIA· 1 shared D. Bourges· 1 shared E. Senechal· 1 shared E. Vigne· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

C. Barjon

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2 papers

Recent·Most cited

Targeting human γδ T cells as a potent and safe alternative to pan-T cells bispecific cell engagers

L. Boutin, C. Barjon, L. Lafrance, E. Senechal, D. Bourges, E. Vigne, E. Scotet

This study compares the antitumor activity of TCEs targeting conventional β T cells and unconventional γδ T cells, finding γδ T cells are more effective and safer.

bioRxiv · Jul 10, 2023Immunology

A dramatic impairment of the antitumor activity of human Vgamma9Vdelta2 T cells is induced by TGF-beta through significant phenotype, transcriptomic and metabolic changes

C. RAFIA, C. LOIZEAU, O. RENOULT, C. HARLY, C. PECQUEUR, N. JOALLAND, E. SCOTET

This study shows TGF-beta impairs Vgamma9Vdelta2 T cell antitumor activity through phenotypic, transcriptomic, and metabolic changes in vitro.

bioRxiv · Sep 22, 2022 · PreprintImmunology