Activation and inhibition of the C-terminal kinase domain of p90 ribosomal S6 kinases
M. U. Fruergaard, C. J. F. Nielsen, C. Rosada, L. Iversen, J. L. Andersen, P. Nissen
The paper characterizes the activation mechanism of the C-terminal kinase domain of RSKs and develops constitutively active variants for inhibitor testing.
bioRxiv · Feb 18, 2022Biochemistry