T Cell Deficiency Precipitates Antibody Evasion and Emergence of Neurovirulent Polyomavirus
M. D. Lauver, K. N. Ayers, S. N. Carey, C. S. Specht, C. S. Abendroth, A. E. Lukacher
The paper shows that T cell deficiency allows JCPyV to develop antibody-escape mutations, leading to neurovirulent variants.
bioRxiv · Feb 25, 2022Immunology