Multiscale profiling of enzyme activity in cancer
A. P. Soleimany, J. D. Kirkpatrick, C. S. Wang, A. M. Jaeger, S. Su, S. Naranjo, Q. Zhong, C. M. Cabana, T. Jacks, S. Bhatia
This paper develops methods to measure enzyme activity in cancer across multiple scales, revealing protease dysregulation and dynamic interactions between tumor cells and their microenvironment.
bioRxiv · Nov 11, 2021 · PreprintBioengineering