Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform
S. Naranjo, C. M. Cabana, L. M. LaFave, P. M. Westcott, R. Romero, A. Ghosh, L. Z. Liao, J. M. Schenkel, I. Del Priore, A. Bhutkar, D. Yang, T. Jacks
This study develops a reliable alveolar type 2 organoid platform to model diverse genetic subtypes of lung adenocarcinoma in vitro and in vivo.
bioRxiv · Dec 7, 2021 · PreprintCancer Biology