Syndecan-3 enhances anabolic bone formation through WNT signalling
F. M. Johnson de Sousa Brito, A. Butcher, A. Pisconti, B. Poulet, A. Prior, G. Charlesworth, C. Sperinck, M. Scotto di Mase, G. Bou-Gharios, R. J. van 't Hof, A. Daroszewska
This study shows that Syndecan-3 promotes bone formation by enhancing WNT signaling in osteoblasts, and its absence leads to osteoporosis-like features in mice.
bioRxiv · Nov 19, 2019 · PreprintCell Biology