Matrix Gla Protein acts as a driver of stemness and tumor initiation in ovarian cancer
V. Nieddu, V. Melocchi, C. Battistini, G. Franciosa, M. Lupia, C. Stellato, G. Bertalot, J. V. Olsen, N. Colombo, F. Bianchi, U. Cavallaro
This study identifies Matrix Gla Protein (MGP) as a driver of stemness and tumor initiation in ovarian cancer by promoting Hedgehog signaling and enhancing tumor-initiating capacity.
Cell Death & Disease · Mar 28, 2023Peer-reviewedCancer Biology