Author

C. T. French

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

A. N. Jones· 2 shared E. W. Settles· 2 shared H. E. Nunnally· 2 shared K. E. Zarn· 2 shared N. E. Stone· 2 shared P. S. Keim· 2 shared S. A. Jaramillo· 2 shared S. Knudsen· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersMicrobiology

A. N. Jones

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3 papers

Recent·Most cited

The PAAR5 Protein of a Polarly-Localized Type VI Secretion System (T6SS-5) is Required for the Formation of Multinucleated Cells (MNCs) and Virulence by Burkholderia pseudomallei.

C. T. French, P. L. Bulterys, J. A. Ceja-Navarro, D. Deshazer, K. R. Ng

This study identifies PAAR5 as essential for cell fusion and virulence in Burkholderia pseudomallei by disrupting T6SS-5-mediated fusogenic activity.

bioRxiv · Feb 9, 2023 · PreprintMicrobiology

Stenoparib, an inhibitor of cellular poly (ADP-ribose) polymerases (PARPs), blocks in vitro replication of SARS-CoV-2 variants

K. E. Zarn, S. A. Jaramillo, A. R. Zapata, N. E. Stone, A. N. Jones, H. E. Nunnally, E. W. Settles, K. Ng, P. S. Keim, S. Knudsen, P. M. Nuijten, A. S. Tijsma, C. T. French

This study shows that stenoparib inhibits SARS-CoV-2 variants in vitro, with EC50 values ranging from 4.1 to 24.1 M, and combination with remdesivir enhances antiviral effects.

bioRxiv · Nov 3, 2021Microbiology

Stenoparib, an inhibitor of cellular poly (ADP-ribose) polymerase (PARP), blocks replication of the SARS-CoV-2 human coronavirus in vitro.

N. E. Stone, S. A. Jaramillo, A. N. Jones, A. J. Vazquez, M. Martz, L. M. Versluis, M. O. Raniere, H. E. Nunnally, K. E. Zarn, R. Nottingham, J. W. Sahl, D. M. Wagner, S. Knudsen, E. W. Settles, P. S. Keim, C. T. French

This paper evaluates stenoparib, a PARP inhibitor, for antiviral activity against SARS-CoV-2 and other coronaviruses in vitro, showing dose-dependent suppression and potential synergy with remdesivir.

bioRxiv · Nov 12, 2020 · PreprintMicrobiology