The PAAR5 Protein of a Polarly-Localized Type VI Secretion System (T6SS-5) is Required for the Formation of Multinucleated Cells (MNCs) and Virulence by Burkholderia pseudomallei.
C. T. French, P. L. Bulterys, J. A. Ceja-Navarro, D. Deshazer, K. R. Ng
This study identifies PAAR5 as essential for cell fusion and virulence in Burkholderia pseudomallei by disrupting T6SS-5-mediated fusogenic activity.
bioRxiv · Feb 9, 2023 · PreprintMicrobiology