Comparative analysis of chemical cross-linking mass spectrometry data indicates that protein STY residues rarely react with N-hydroxysuccinimide ester cross-linkers
Y. Cao, X.-T. Liu, P.-Z. Mao, C. Tarn, M.-Q. Dong
The paper evaluates the reliability of STY cross-link identifications in CXMS and finds they have high false discovery rates, often misclassified as K-K or K-mono-links.
bioRxiv · Jan 17, 2023Biochemistry