Interleukin-1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification
H.-W. Tseng, I. Kulina, D. Girard, J. Gueguen, C. Vaquette, M. Salga, W. Fleming, B. Jose, S. Millard, A. Pettit, K. Schroder, G. Thomas, L. Wheeler, F. Genet, S. Banzet, , J.-P. Levesque
This study shows IL-1 signaling promotes neurogenic heterotopic ossification in mice and humans by activating fibro-adipogenic progenitors.
bioRxiv · Oct 19, 2021Physiology