Author

J.-P. Levesque

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. C. Wu· 2 shared A. Pettit· 2 shared A. R. Pettit· 2 shared A. Sehgal· 2 shared B. Jose· 2 shared D. A. Hume· 2 shared D. Girard· 2 shared F. Genet· 2 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

A. C. Wu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Spinal cord injury reprograms muscle fibro-adipogenic progenitors to formheterotopic bones within muscles

H.-W. Tseng, D. Girard, K. Alexander, S. Millard, F. Torossian, A. Anginot, W. Fleming, J. Gueguen, M.-E. Goriot, D. Clay, B. Jose, B. Nowlan, A. Pettit, M. Salga, F. Genet, , J.-P. Levesque

This study identifies fibro-adipogenic progenitors (FAPs) as the cells-of-origin for neurogenic heterotopic ossifications (NHO) following spinal cord injury, showing their reprogramming into osteoblasts.

bioRxiv · Nov 4, 2021 · PreprintPathology

Interleukin-1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification

H.-W. Tseng, I. Kulina, D. Girard, J. Gueguen, C. Vaquette, M. Salga, W. Fleming, B. Jose, S. Millard, A. Pettit, K. Schroder, G. Thomas, L. Wheeler, F. Genet, S. Banzet, , J.-P. Levesque

This study shows IL-1 signaling promotes neurogenic heterotopic ossification in mice and humans by activating fibro-adipogenic progenitors.

bioRxiv · Oct 19, 2021Physiology

Fragmentation of macrophages during isolation confounds analysis of single cell preparations from mouse hematopoietic tissues

S. M. Millard, O. Heng, K. S. Opperman, A. Sehgal, K. M. Irvine, S. Kaur, K. M. Summers, C. J. Sandrock, A. C. Wu, G. W. Magor, L. Batoon, A. C. Perkins, J. E. Noll, A. C. Zannettino, D. P. Sester, , A. R. Pettit

The paper identifies macrophage fragmentation during isolation as a confounding factor in single-cell analysis of mouse hematopoietic tissues, revealing its impact on marker expression and function.

bioRxiv · Apr 28, 2021Immunology

Stable colony stimulating factor 1 fusion protein treatment increases HSC pool and enhances their mobilisation in mice.

S. Kaur, A. Sehgal, A. C. Wu, S. M. Millard, L. Batoon, M. Ferrari-Cestari, J.-P. Levesque, D. A. Hume, L. J. Raggatt, A. R. Pettit

CSF1-Fc treatment expands the HSC pool and enhances their mobilization in mice, improving transplantation outcomes.

bioRxiv · Sep 13, 2020Cell Biology