Supporting materials: Endothelial cells differentiated from patient dermal fibroblast-derived induced pluripotent stem cells resemble vascular malformations of Port Wine Birthmark
V. Nguyen, C. Gao, M. Hochman, J. Kravitz, E. Chen, H. Friedman, C. Wenceslau, D. Chen, Y. Wang, J. S. Nelson, A. G. Jegga, W. Tan
This study generates iPSCs from PWB fibroblasts and differentiates them into ECs that recapitulate disease phenotypes, identifying dysregulated pathways and genes involved in vascular malformations.
bioRxiv · Jul 2, 2023 · PreprintCell Biology