In situ structural insights into the excitation contraction coupling mechanism of skeletal muscle
J. Xu, C. Liao, C.-c. Yin, G. Li, Y. Zhu, F. Sun
This study reveals the nanometre-resolution structure of the RyR1-DHPR supercomplex in skeletal muscle triads, showing their unique arrangement and physical coupling mechanism for excitation-contraction coupling.
bioRxiv · Aug 26, 2023 · PreprintBiophysics