Author

C.-H. Zhang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:plant (other)· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

X.-B. Wang· 2 shared Y.-L. Liu· 2 shared Z.-G. Xu· 2 shared Z.-Y. Guo· 2 shared A. Bais· 1 shared B. Ganapathy· 1 shared B. Kuhn· 1 shared C. Guillermier· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

X.-B. Wang

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Author profile →

4 papers

Recent·Most cited

An efficient peptide ligase engineered from a bamboo asparaginyl endopeptidase

X.-B. Wang, C.-H. Zhang, T. Zhang, H.-Z. Li, Y.-L. Liu, Z.-G. Xu, G. Lei, C.-J. Cai, Z.-Y. Guo

The paper engineers a bamboo-derived peptide ligase with improved activity by modifying its activation mechanism.

bioRxiv · Sep 7, 2023Biochemistry

Development of a novel bioluminescent activity assay for peptide ligases

C.-H. Zhang, X.-X. Shao, X.-B. Wang, L.-L. Shou, Y.-L. Liu, Z.-G. Xu, Z.-Y. Guo

The paper develops a bioluminescent assay to identify and characterize peptide ligases, finding that several plant species likely express these enzymes.

bioRxiv · Nov 1, 2021 · PreprintBiochemistry

Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2

M. M. Ghahremanpour, J. Tirado-Rives, M. Deshmukh, J. A. Ippolito, C.-H. Zhang, I. Cabeza de Vaca, M.-E. Liosi, K. S. Anderson, W. L. Jorgensen

The paper identifies 14 known drugs that inhibit SARS-CoV-2 main protease, with five showing IC50 values below 40 μM.

bioRxiv · Aug 28, 2020Pharmacology & Toxicology

Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment

H. Liu, C.-H. Zhang, N. Ammanamanchi, S. Suresh, C. Lewarchik, K. Rao, G. M. Uys, L. Han, M. Abrial, D. Yimlamai, B. Ganapathy, C. Guillermier, N. Chen, M. Khaladkar, J. Spaethling, , B. Kuhn

This study shows that β-adrenergic receptor signaling regulates cardiomyocyte cytokinesis, and β-blockers like propranolol can enhance division in ToF/PS cardiomyocytes, potentially improving heart function in CHD patients.

bioRxiv · Oct 4, 2019Cell Biology