Author

C.-w. Chung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C. Deane· 2 shared O. Crook· 2 shared A. Brewster· 1 shared A. C. Pearce· 1 shared A. Denis· 1 shared A. Dossang· 1 shared A. M. Jagger· 1 shared A. Olszewski· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

C. Deane

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Author profile →

5 papers

Recent·Most cited

Inferring residue level hydrogen deuterium exchange with ReX

O. Crook, N. Gittens, C.-w. Chung, C. Deane

ReX infers residue-level hydrogen deuterium exchange from HDX-MS data, showing improved performance in predicting unseen data and quantifying conformational changes in proteins.

bioRxiv · Apr 12, 2024 · PreprintBiochemistry

Microscopy-guided subcellular proteomic discovery by high-speed ultra-content photo-biotinylation

Y.-D. Chen, C.-W. Chang, C. H. Y. Cheung, H.-J. Chang, Y.-D. Sie, C.-W. Chung, C.-K. Huang, C.-C. Huang, W. M. Chong, Y.-P. Liu, Y.-C. Lin, H.-J. J. Kai, P.-J. Wang, J.-C. Liao

This paper introduces a microscopy-guided proteomics method called optoproteomics to identify subcellular proteins with high spatial precision and sensitivity.

bioRxiv · Dec 27, 2023 · PreprintCell Biology

A functional Bayesian model for hydrogen-deuterium exchange mass-spectrometry

O. Crook, C.-w. Chung, C. Deane

The paper introduces a Bayesian framework for analyzing HDX-MS data to improve uncertainty quantification and model selection in protein conformational studies.

bioRxiv · Jul 18, 2022Biophysics

Development of a small molecule that corrects misfolding and increases secretion of Z α1-antitrypsin

D. Lomas, J. A. Irving, C. Arico-Muendel, S. Belyanskaya, A. Brewster, M. J. B. Brown, C.-w. Chung, H. Dave, A. Denis, N. Dodic, A. Dossang, P. Eddershaw, D. Klimaszewska, I. Haq, D. Holmes, , A. C. Pearce

This study identifies a small molecule that stabilizes Z α1-antitrypsin, reduces polymerization, and increases its secretion in cells and mice.

bioRxiv · Jul 26, 2020Pharmacology & Toxicology

Significantly different expression levels of microRNAs associated with vascular invasion in hepatocellular carcinoma and their prognostic significance after surgical resection

S. K. Song, W. Y. Jung, S.-K. Park, C.-W. Chung, Y. K. Park

This study identifies miRNAs differentially expressed in hepatocellular carcinoma with vascular invasion and shows their association with poor prognosis after surgical resection.

bioRxiv · May 1, 2019Cancer Biology