Author

Caihao Nie

University of California, Irvine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Hajime OzakiiD· 2 shared Jiya Dalal· 2 shared Kaori Shiraiwa· 2 shared Matthew Jung Min Noh· 2 shared Momoko WatanabeiD· 2 shared Yuan‐Chen TsaiiD· 2 shared Ali MohraziD· 1 shared Axel A. AlmetiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBioengineering

Hajime OzakiORCID

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Author profile →

2 papers

Recent·Most cited

Spatial engineering of posterior signaling centers in cerebral organoids via controlled morphogen exposure within hydrogels

Harrison Jeong, Hajime Ozaki, Yuan‐Chen Tsai, Caihao Nie, Skylar R. Foust, Kaori Shiraiwa, Ziye Zhuang, Doyle Miller, Matthew Jung Min Noh, Jiya Dalal, Aya Galal Salem, Christine Hien Vu, Ali Mohraz, Momoko Watanabe, Herdeline Ann M. Ardoña

This paper introduces a hydrogel platform to spatially engineer posterior signaling centers in cerebral organoids through controlled morphogen exposure, improving spatial organization and cellular diversity.

bioRxiv · Oct 28, 2026 · PreprintBioengineering

Morphogen-guided neocortical organoids recapitulate regional areal identity and model neurodevelopmental disorder pathology

Yuan‐Chen Tsai, Hajime Ozaki, Xinyi Wang, Axel A. Almet, Isabel Fleming, Kaori Shiraiwa, Matthew Jung Min Noh, Caihao Nie, Sunnyana Trejo, Bret Kiyoshi Sugita, Jiya Dalal, Ruben Alberto Gonzalez, Briana De Jesus, Gregory Li-Min Chen, Michael J. Gandal, , Momoko Watanabe

This study develops a method to generate neocortical organoids with distinct anterior-posterior molecular signatures and uses them to model Fragile X Syndrome pathology.

bioRxiv · Sep 2, 2025 · PreprintDevelopmental Biology