Author

Isabel Fleming

University of California, Irvine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Axel A. AlmetiD· 1 shared Bret Kiyoshi Sugita· 1 shared Briana De Jesus· 1 shared Caihao Nie· 1 shared Gregory Li-Min Chen· 1 shared Hajime OzakiiD· 1 shared Jiya Dalal· 1 shared Kaori Shiraiwa· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperDevelopmental Biology

Axel A. AlmetORCID

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1 paper

Recent·Most cited

Morphogen-guided neocortical organoids recapitulate regional areal identity and model neurodevelopmental disorder pathology

Yuan‐Chen Tsai, Hajime Ozaki, Xinyi Wang, Axel A. Almet, Isabel Fleming, Kaori Shiraiwa, Matthew Jung Min Noh, Caihao Nie, Sunnyana Trejo, Bret Kiyoshi Sugita, Jiya Dalal, Ruben Alberto Gonzalez, Briana De Jesus, Gregory Li-Min Chen, Michael J. Gandal, , Momoko Watanabe

This study develops a method to generate neocortical organoids with distinct anterior-posterior molecular signatures and uses them to model Fragile X Syndrome pathology.

bioRxiv · Sep 2, 2025 · PreprintDevelopmental Biology