A broad-spectrum phage-encoded mechanism to disarm bacterial type IV filaments
Nathan A. Roberge, Paankhi Dave, Véronique L. Taylor, Taylor J. Ellison, Callum Myers, Courtney K. Ellison, Karen L. Maxwell, Lori L. Burrows
This paper identifies Aqs1, a phage-encoded protein that inhibits type IV pilus function in multiple Gram-negative bacteria by targeting the PilB ATPase.
PLoS Pathogens · Jul 27, 2026Peer-reviewedMicrobiology